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There are several medications that, when taken with a thiazide diuretic, can result in serious side effects.
Hydrochlorothiazide and then stopping its use may for some time cause symptoms like headache, nausea, vomiting, dizziness and lethargy.
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Studies V and VI had no placebo group, so effects described below are not all attributable to irbesartan or hydrochlorothiazide.
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